DeCS Server - List Exact Term

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DeCS

Descriptor Inglés:

Activin Receptors

Descriptor Español:

Receptores de Activinas

Descriptor Portugués:

Receptores de Ativinas

Sinónimos Inglés:

Activin Receptor-Like Kinases

Categoría:

Definición Inglés:

Receptors for ACTIVINS are membrane protein kinases belonging to the family of PROTEIN-SERINE-THREONINE KINASES, thus also named activin receptor-like kinases (ALK's). Activin receptors also bind TRANSFORMING GROWTH FACTOR BETA. As those transmembrane receptors of the TGF-beta superfamily (RECEPTORS, TRANSFORMING GROWTH FACTOR BETA), ALK's consist of two different but related protein kinases, Type I and Type II. Activins initiate cellular signal transduction by first binding to the type II receptors (ACTIVIN RECEPTORS, TYPE II ) which then recruit and phosphorylate the type I receptors (ACTIVIN RECEPTORS, TYPE I ) with subsequent activation of the type I kinase activity.

Nota Histórica Inglés:

2002; use ACTIVIN RECEPTORS (NM) 1991-2001

Calificadores Permitidos Inglés:

Número del Registro:

36116

Identificador Único:

D029404

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